iGenics Ingredients: Dose-by-Dose Analysis

Lutein — 20mg

Lutein is a carotenoid pigment that the body cannot produce on its own — it must come from diet or supplementation. It accumulates specifically in the macula, where it functions as a natural blue-light filter and antioxidant. The AREDS-2 clinical trial used 10mg; iGenics provides 20mg, double that amount. A 2019 study published in the journal Nutrients found that higher Lutein intake correlates with greater macular pigment optical density, a key biomarker for AMD risk.

Zeaxanthin — 2mg

Zeaxanthin works alongside Lutein in the macula, with research suggesting it concentrates more centrally while Lutein spreads more peripherally — together they provide more complete macular coverage. The 2mg dose in iGenics matches the AREDS-2 clinical dose precisely.

Bilberry Extract — 480mg

Bilberry's anthocyanosides are powerful antioxidants studied for their effect on the microcirculation supplying the retina. Most commercial eye supplements use 50-100mg of Bilberry; iGenics' 480mg dose sits well above that range, in line with the doses used in clinical studies examining night vision and eye fatigue outcomes.

Saffron

Saffron's active compounds, crocin and crocetin, have been the subject of growing ophthalmological research. A study in Investigative Ophthalmology & Visual Science found that saffron supplementation produced measurable improvements in visual function among patients with early AMD over a several-month period, likely through neuroprotective effects on photoreceptor cells.

Ginkgo Biloba

Ginkgo is one of the most studied herbal extracts for circulation. Applied to eye health, improved blood flow to the optic nerve and retina translates to better oxygen and nutrient delivery — particularly relevant for older adults where vascular efficiency naturally declines.

Turmeric — 350mg

Curcumin, turmeric's active compound, is a well-documented anti-inflammatory agent. Chronic low-grade inflammation in ocular tissue is increasingly recognized as a contributing factor in both AMD and glaucoma, making this a relevant inclusion at a therapeutically meaningful 350mg dose.

Supporting Vitamins & Minerals

Vitamin C and Vitamin E are the core antioxidant vitamins from the AREDS-2 protocol. Vitamin A supports rhodopsin production, the pigment enabling low-light vision. Zinc is critical for retinal health, while Copper is included specifically to prevent the copper deficiency that high-dose zinc can otherwise cause. Black Pepper Extract (Bioperine) is included to improve absorption of the other active compounds.

Frequently Asked Questions